Memory decline associated with physiological aging and age-related neurological disorders has a direct impact on quality of life for seniors.With demographic aging, the assessment of cognitive functions is gaining importance, as early diagnosis can lead to more effective cognitive interventions.In comparison to classic paper-and-pencil approaches,
Abstract Multiple complex intracellular cascades contributing to Hunter syndrome (mucopolysaccharidosis type II) pathogenesis have been recognized and documented in the past years.However, the hierarchy of early cellular abnormalities leading to irreversible neuronal damage is far from being completely understood.To tackle this issue, we have gener
Pancreatic ductal adenocarcinoma (PDAC) is notorious for a dense fibrotic stroma that is interlaced with a collagen-based extracellular matrix (ECM) that plays an important role in tumor biology.Traditionally thought to only provide a physical barrier from host responses and systemic chemotherapy, new studies have demonstrated that the ECM maintain
The paper considers the design of a hydraulic drive of an additional electric Stainless Steel Cleaner generator installed on a car, which should provide stable electrical power to consumers with standard parameters (voltage 220 (380) V, frequency 50 Hz).To solve this problem a hydraulic regulator for a hydraulic drive connected to the motor shaft o
In natural populations, quantitative trait dynamics often do not appear to follow evolutionary predictions.Despite abundant examples of natural selection acting on heritable traits, conclusive evidence for contemporary adaptive evolution remains rare for wild vertebrate populations, and phenotypic Brushes stasis seems to be the norm.This so-called